CBDa vs CBD: The Combination is Better Than Either Alone
Posted on June 5th, 2022
In the debate of CBDa vs CBD: the combination is better than either alone. But what is CBDa, and why does it work better with CBD? Here’s the crucial information you need.
Now, you may already know that CBD is a compound we find in the Cannabis Sativa plants. You also may have heard it comes with a host of potential health benefits. From helping anxiety symptoms and joint pain, it may manage several health problems. Most importantly, thousands of people love consuming CBD because it doesn’t have side effects like THC. (That’s the compound in Cannabis Sativa plants that makes you feel high.)
While CBD is at peak popularity, we’ve been researching another cannabinoid with similar characteristics. We now know that Cannabidiolic acid or CBDa may offer similar benefits. Even better? University research suggests that CBDa and CBD actually work better together than alone. Like the entourage effect, but with just the two of them.
CBD and its benefits
The Cannabis Sativa plant contains hundreds of different compounds. And each has its own potential benefits. But a big advantage of CBD is that it doesn’t intoxicate you. Even if you buy a full-spectrum product, US manufacturers make sure the CBD contains no more than 0.3% THC. This makes the psychoactive element almost negligible, thereby eliminating the risks of intoxication.
But how might CBD benefit your body? Well, the endocannabinoid system (ECS) plays a crucial role in cannabinoid effects. It’s responsible for restoring your body’s homeostasis or natural balance. And it contains two receptors: CB1 and CB2. CBD interacts with CB2 receptors in your peripheral nervous system. And they influence inflammation and pain. It also interacts with CB1 receptors, found primarily in the central nervous system. They’re in charge of mood, appetite, movement, coordination, and memory.
Importantly, CBD doesn’t attach directly to receptors. As a result, they may influence ECS-controlled symptoms. But they won’t overwhelm receptors, which is why you won’t get high from cannabidiol.
What is CBDa?
CBDa is an acidic precursor of CBD. For that reason, it’s most abundant in the early stages of plant development. Because that’s when hemp first starts producing flowers. But it’s difficult to extract a lot of CBDa. Because, with heat, it turns into CBD. So when you start processing raw plant matter, you’ll lose a lot of cannabidiolic acid.
Initially, scientists didn’t expect CBDa to have health benefits. They thought it didn’t interact with endocannabinoid receptors. For that reason, they immediately started decarboxylation, heating plant matter to produce CBD. But according to recent research, CBDa may offer its own health benefits.
How does this work? Instead of connecting with your ECS, it works with an enzyme called COX-2. (The enzyme controls inflammation in your body.) CBDa may also increase serotonin levels in your body. Serotonin is the ‘happy hormone’ because it contributes to your mood and wellbeing.
Now, that all sounds great, but CBDa has one big drawback: it remains unstable in its original state. For that reason, when it comes to CBDa vs CBD: the combination is better than either alone. Because, according to research, combining both cannabinoids allows each to offer its own benefits. And it also amplifies each others effects in your body.
Potential CBDa Benefits
As we reviewed earlier, CBDa doesn’t interact with the endocannabinoid system. Instead, it bypasses the receptors and interacts with specific enzymes to provide the following potential health benefits:
CBDa interacts with COX-1 and COX-2 enzymes that spread inflammation throughout the body. In doing so, it may reduce and control chronic or acute inflammation. And that’s important, because chronic inflammation contributes to various auto-immune disorders, including multiple sclerosis and rheumatoid arthritis.
Without inhibition, your body can release a high percentage of inflammatory enzymes. When this happens, white cells may attack your body’s cells and cause immense pain. Fortunately, CBDa may control that inflammation by limiting the release of inflammatory enzymes.
Consuming CBD helps many people reduce their anxiety symptoms. In addition to CBD, CBDa can also affect your mood just before an anxiety attack. It works with 5-HT1A, a serotonin receptor. This receptor is primarily responsible for controlling vomiting and nausea, but also regulates your body’s serotonin levels.
It influences your mood and may help control depression and anxiety. CBDa’s interaction with serotonin receptors seems to have the same working mechanism as SSRI (serotonin reuptake inhibitor) antidepressant medications. But here, the advantage of CBDa is that it doesn’t come with the side effects that these medicines often trigger.
● Seizures and Cell Disorders
Initial studies suggest that CBDa may be more effective at managing epileptic seizures than CBD. But researchers still need time to compare the effects of both compounds. So with CBDa vs CBD: the combination is better than either alone. At least until we see which cannabinoid wins out in this scenario.
A few studies also suggest that CBDa may be helpful during cancer treatment. (Remember, though, that existing research only explored effects on isolated cells.) Still, some scientists believe that CBDa can prevent the migration of MDA-MB-231, a highly aggressive cell line that contributes to breast cancer.
Apart from the above potential health benefits, CBDa also has anti-oxidant, analgesic, anti-bacterial, anti-inflammatory, and anti-nausea properties.
CBDa vs CBD: the combination is better than either alone
Both CBD and CBDa provide respective health benefits. And, left alone, CBDa eventually turns into CBD. (Though it still contains some dormant compounds, even after activating.) Also, CBDa contains more terpenes than CBD, so it may be slightly more effective in certain settings. As a result, when you combine the two, your body can absorb all the activated compounds, as well as terpenes, CBDa, and CBD.
Currently, our research reveals that CBDa and CBD work better when consumed together. That’s why all of our Tanasi CBD products contain a patent-pending ratio of each cannabinoid. Backed by years of scientific research, we’ve learned that in the debate of CBDa vs CBD: the combination is better than either alone. So we’ve made it possible for you to get the best of both worlds, all in one full-spectrum hemp extract.