CBN And CBC: Benefits of The Lesser-known Cannabinoids


Posted on November 5th, 2020

Many in the US know of either CBD or THC due to the popularity of hemp and cannabis’ products. Cannabidiol (CBD) and tetrahydrocannabinol (THC) are the most popular cannabinoids worldwide. However, the cannabis world isn’t just about those two cannabinoids at all.

You may not realize the vast number of hemp-derived products available yet since the industry is still growing at the moment. Other cannabinoids exist and are currently under research. They have shown promising results thus far. THC, CBD, CBG, CBN, and CBC are some of the other cannabinoids abundant inside the cannabis and hemp plants. This class of compounds is known as cannabinoids. They are responsible for the therapeutic benefits associated with cannabis consumption.

What Are Cannabinoids?

The cannabis plant contains active compounds that induce various effects on the body. These compounds are called cannabinoids. They are extracted in various forms, including broad-spectrum oil and isolate. Still, you can consume these compounds directly from the plant if you so choose.

Different strains of cannabis contain different cannabinoids. For this reason, you need to research the strains that are high in the cannabinoids you prefer. You experience the therapeutic effects of these compounds during their interaction with the Endocannabinoid System (ECS). More specifically, their interactions with the cannabinoid receptors CB1 and CB2 inside your body.

So far, there are over 110 cannabinoids identified. Each compound has its unique properties and benefits to offer you. They can assist you in managing mental health, pain, sleep, inflammation, and cognitive function.

Classes of Cannabinoids

Cannabinoids fall into the following subclasses:

  • Major cannabinoids: Tetrahydrocannabinol (THC) and Cannabidiol (CBD).
  • Minor cannabinoids: Cannabinol (CBN), Cannabigerol (CBG), Cannabinodiol (CBDL), and Cannabichromene (CBC).
  • Other cannabinoids: Cannabicyclol (CBL), Cannabitriol (CBT), and Cannabielsoin (CBE).

The body’s chief regulatory network, known as the endocannabinoid system, interacts with cannabinoids through cannabinoid receptors. These receptors are on the cells’ surface area. The molecules of cannabinoids attach themselves to CB1 and CB2 receptors in different parts of the nervous system.

Cannabinoid effects are dependent on the part of the brain involved. For instance, the limbic system affects memory and psychomotor performance. Side effects of these compounds also affect pain response and pleasure.

What Are the Differences Between Cannabinoids?

The psychoactive properties of various cannabinoids are the key differences there are between these compounds. CBC, CBG, and CBD aren’t psychoactive. CBN, THC, and CBDL, on the other hand, have minor varying ranges of psychoactivity.

The Body’s Interaction with Cannabinoids: What Happens?

The body doesn’t just interact with CBD and THC. It interacts with many cannabinoids, including CBN and CBC. Each body responds differently when exposed to cannabinoids.

The endocannabinoid system (ECS) helps the body maintain a healthy internal environment. It consists of receptors that help to self-regulate biological processes. Cannabinoid receptors exist in nearly all major organ systems, including the gut, spinal cord, and brain. CB1 receptors are highly concentrated within the central nervous system and the brain, while CB2 receptors are associated with the immune system.

The ECS is present in all invertebrates and vertebrates. This interconnecting network is a physiological system that helps maintain homeostasis. It regulates neurological functions, consequently ensuring all cellular processes are operating normally. Simply put, the ECS helps us to adapt to environmental settings like fear, hunger, and stress.

The interaction of cannabinoids with the ECS system enables cannabinoid receptors to affect critical body processes. Pain, immune response, memory, appetite, mood, reproductive functions, cognitive processes, and body temperature. The interaction between individual cannabinoids and the endocannabinoid system derives specific therapeutic effects for users of cannabis and hemp-derived products.

As said before, there are over 114 different cannabinoids identified so far. Most people aren’t aware of the effects of lesser-known cannabinoids like CBN and CBC. Thanks to the complex molecular structure of cannabis, more cannabinoids are likely to be discovered through research.

What is CBN?CBN And CBC - CBN helps a young woman fall asleep easily

CBN (cannabinol) is a far less famous cannabinoid. It isn’t easily extractable from the cannabis plant. The synthesis of CBN happens after the degradation of THC; cannabinol then forms as a by-product.

Thus, CBN comes to be due to THC gradually degrading as the cannabis plant ages. This degradation process triggers due to exposure to heat and UV rays. The content of CBN, even in aged cannabis flowers, is typically less than 1%. Both CBN and THC have similar chemical compositions, but CBN is less psychoactive. CBN doesn’t develop from CBGA (cannabigerolic acid) like many other cannabinoids. Instead, it is a metabolite of THC.

What Are the Benefits of Using CBN?

Cannabinol is consistently showing to be one of the best cannabinoids so far. Some people view THC degrading into CBN as a bad thing. However, there are various benefits to CBN that people can take advantage of to manage multiple conditions.


Today, many people use CBN to help them sleep. This compound contains powerful sedative properties. It can manage insomnia. CBN may be the right cannabinoid for you if you need some quality sleep.

You can think of CBN as the sleep version of CBD, making it the best cannabinoid to use for people living with insomnia. The ‘entourage effect’ has led to a flux in demand for combined cannabinoid product formulations worldwide. Of those, a partial CBN infusion for sleep seems poised to become very popular.


Various conditions negatively affect people’s eating patterns, including cancer and anorexia. Research has shown that CBN can help stimulate appetite. Studies done on rats using CBD, THC, and CBN showed that CBN could increase the amount of food consumed as well as boost appetite.


Glaucoma patients risk blindness due to damage to the optic nerves. Blind spots develop as nerve deterioration progresses. Worldwide, glaucoma is the second leading cause of blindness. The condition damages retinal ganglion cells, eventually leading to their death.

CBN helps to lower intraocular pressure, which causes blindness. It helps to protect neurons located at the back of the eye. This compound has the optimal effect of neuroprotection.

Potent Antibiotic

CBG, CBN, and CBC, when used together, have shown the ability to treat infections such as methicillin-resistant Staphylococcus aureus effectively. CBN also comes in handy when slowing the progression of Lou Gehrig’s disease or amyotrophic lateral sclerosis (ALS). One study was able to delay ALS symptoms in mice by using cannabinol in their treatment.

What Is CBC?CBN And CBC - CBC helps the brain generates new neurons

So far, there is not much info about CBC or cannabichromene compared to CBD and THC. Structurally, this non-psychoactive compound that first appeared in 1966 is similar to other cannabinoids. This compound forms when CBG/CBGA breaks down after ultraviolet light or heat exposure. CBG/CBGA disintegrates into CBCA, which later converts into CBC.

Cannabichromene, a non-intoxicating compound, binds with TRPV1 or vanilloid receptor 1 and TRPA1 or transient receptor potential ankyrin 1. These receptors play an essential role in inflammation and pain transmission signals. It can be critical in treating conditions such as osteoarthritis, more so when combined with THC.

What Are the Benefits of Using CBC?

Brain Protection

CBC promotes neurogenesis. This process involves the formation of new brain neurons. CBC helps in the growth of brain cells responsible for learning and memory. You risk developing neurodegenerative conditions such as Alzheimer’s disease and Parkinson’s disease when your brain stops producing new brain cells.

Inflammatory Pain

Data shows that CBC modulates vanilloid receptor 1 activity within the brain. TRPV1 has links mainly to the inflammatory pain processes. CBC can be used to fight inflammation on its own. Still, it can be combined with THC to reduce inflammation.

Acne Treatment

Research has found CBC to have potent antibacterial effects that can help with acne. It can help reduce sebum production in the sebaceous glands. Still, it helps reduce the effects of arachidonic acid on your glands and skin. The overactivity of these glands, which produce oil for your skin, may lead to acne.

Brain Function

CBC promotes the growth of nervous tissue through neurogenesis. A 2013 study proved that CBC helped promote brain tissue growth. It increased the viability of new brain cells. CBC, THC, and CBD also showed mood-boosting benefits when used for depression.


Research has shown that cannabichromene inhibits the uptake of anandamide, helping to fight breast cancer. CBC also has TPSA value, which promotes the cannabinoid molecule’s penetration into the cancer cell’s membrane.

CBN And CBC – Which Cannabinoids Should I Go For?

Different cannabinoids have different unique properties that help to treat and manage various conditions. Thus, you should always choose the cannabinoid which effects better fit with your requirements. For instance, CBN and CBC can manage multiple disorders, including glaucoma, insomnia, inflammation, and depression.

Always consult your physician first. Above all, they can provide professional advice regarding the best treatment plan for you. In other words, talking first with your physician about incorporating cannabinoids into your routine is an act of self-care, so don’t skip on it!

CBN And CBC – The Takeaway

The therapeutic promises of CBN and CBC require more research. Even so, many users are already experiencing their benefits. Cannabinoids react differently to every user. You have to find the right dosage of these compounds to experience optimal results.

For that, you’ll require the right supplier once you’ve settled on which cannabinoids you want to use. Never compromise on quality. At Tanasi, we have access to the best full-spectrum CBD hemp products with proven quality. We are always here for all your cannabinoid-related needs.

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